PR40A Polyclonal Antibody, 20ul

The WW domains are essential for localization to nuclear speckles.,Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). May be involved in pre-mRNA splicing.,sequence Contaminating sequence. Potential poly-A sequence starting in position 409.,sequence Contaminating sequence. Potential poly-A sequence.,Belongs to the PRPF40 family.,Contains 2 WW domains.,Contains 5 FF domains.,subunit:Interacts with the N-terminus of HTT. Interacts with the phosphorylated carboxyterminal domain of POLR2A. Interacts with SF1, SRPK1 CARD8, ATBF1 and MECP2 (By similarity). Interacts through the WW domains with formin proline-rich regions and with WASL/N-WASP.,tissue specificity:Widely expressed.,